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Mental fatigue can trick the brain into taking the easy way out

21 Jul 2025
2 min

Cognitive Fatigue and Its Impact on Decision-Making

A recent study, published in the Journal of Neuroscience, highlights how mental fatigue influences decision-making by making tasks seem more demanding and thus preferring easier tasks. Despite offering fewer benefits, mentally exhausted individuals lean towards tasks requiring less effort.

Neurobiological Findings

  • Functional Magnetic Resonance Imaging (fMRI) was used to track brain activity.
  • The dorsolateral prefrontal cortex (dlPFC) was activated during tasks.
  • The right anterior insula evaluated task effort versus reward.
  • Signals from dlPFC representing fatigue influenced the insula's neural activity, altering effort valuation.

Interpretations and Implications

  • Despite feeling fatigued, participants' performance didn’t decrease; instead, they opted for easier tasks.
  • When benefits are clear, people exert effort, but uncertain benefits can alter behavior.
  • Fatigue can influence decisions even in physical tasks, highlighting a possible neurobiological reason for avoiding physical activity when mentally tired.

Broader Impact and Future Research

  • Cognitive fatigue is a symptom in various neurological and psychiatric conditions, but its manifestation is poorly understood.
  • The study paves the way for managing fatigue by understanding its impact on decision-making.
  • Further research will explore the relationship between short-term and long-term fatigue effects and how cognitive capacities are restored.

To mitigate fatigue’s impact on decision-making, taking breaks and reframing tasks are advised strategies.

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