![An infograhic image showing types of Drug-Resistant TB namely, Multidrug Resistant (MDR) TB which is resistant to aleast Isoniazid and Rifampicin; Extensively Drug Resistant (XDR) TB which is resistant to Isoniazid and Rifampicin plus fluoro-quinolone and at least one of the three injectable second-line drugs; and Totally Drug Resistant (TDR) TB which is resistant to all first-line and second-line TB drugs.](https://d2av8kbir6lh9m.cloudfront.net/uploads/Azurue4jp9V2CslMb0pnDR3r6NptUfGvsPcXBedC.png)
New BPaLM regimen consisting of four drugs — Bedaquiline, Pretomanid, Linezolid and Moxifloxacin — has proven to be a safe, more effective and quicker treatment option than previous procedures.
- Earlier, Pretomanid has been approved & licensed for use in India by CDSCO.
- It brings down treatment time to 6 months from earlier duration of 20 months.
- BPaLM regimen was introduced under National TB Elimination Programme and expected to boost the country’s progress to achieve its national goal of ending TB in India by 2025.
About Tuberculosis
- An infectious disease that most often affects lungs and is caused by bacillus Mycobacterium tuberculosis bacteria.
- Bacillle Calmette-Guerin (BCG) vaccine provides immunity against TB.
- As per India TB Report 2024, there were 25.52 lakh notified TB patients in 2023.
Challenges in Tuberculosis Eradication
- Social Stigma leads to delayed diagnosis; High Treatment Costs, Comorbidities with HIV, diabetes; Lack of diagnostics facility in rural areas etc.
Other Initiatives taken for Tuberculosis Eradication
- Pradhan Mantri TB Mukt Bharat Abhiyan provides additional patient support, augment community involvement.
- Ni-kshay Mitra ensures additional diagnostic, nutritional, support to those on TB treatment.
- Nikshay Poshan Yojana provides financial support to TB patients for their nutrition.