Ministry of Science & Technology Introduces 'PPP plus PPP' Model to check diabetes in India | Current Affairs | Vision IAS
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“PPP plus PPP” is a two-tiered collaboration where India’s public and private sectors unite internally to strengthen healthcare infrastructure while simultaneously engaging with international counterparts.

  • The model was introduced on World Diabetes Day (14th November) which was made a global observation by the UN in 2006 and was first established in 1991 by WHO and International Diabetes Federation (non-profit organisation). 

About Diabetes or Diabetes Mellitus (DM)

  • DM is a chronic, metabolic disease that causes elevated blood glucose levels (hyperglycemia)
  • Symptoms: Loss of glucose through urine and formation of harmful compounds known as ketone bodies. 
    • It can cause serious damage to the heart, blood vessels, eyes, kidneys, and nerves. 
  • Major Types 
    • Type 1 (juvenile diabetes or insulin-dependent diabetes): Autoimmune disorder in which insulin producing cells are destroyed by immune system 
    • Type 2: Most common type and usually occurs in adults. Caused when body becomes resistant to insulin or doesn't make enough insulin.
    • Gestational: Develops during pregnancy
  • Prevalence:  Around 830 million people globally have diabetes (around 212 million in India), the majority living in low-and middle-income countries 
  • Treatment Gap: More than 50% lack treatment. 
    • Around 64 million men and 69 million women with untreated diabetes in India are at high risk of developing associated severe complications. 
  • WHO Target:  To halt the rise in diabetes and obesity by 2025

About Insulin 

  • Insulin is a peptide hormone secreted by β-cells of Pancreas. 
  • It plays a major role in the regulation of glucose homeostasis
    • Insulin acts mainly on hepatocytes and adipocytes (cells of adipose tissue), and enhances cellular glucose uptake and utilisation.
  • Nowadays, recombinant human insulin is mainly produced either in E. coli or Saccharomyces cerevisiae. 

 

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